Amongst grownup sufferers presenting to the ED with suspected fever after the COVID-19 vaccination, older sufferers had been much less prone to have a fever upon admission to the ED and had been extra prone to delay their ED go to and require subsequent hospitalization for medical circumstances that had nothing to do with vaccination. These outcomes had been printed in a research in Journal of An infection and Chemotherapy.
On this retrospective, observational research performed between March and September 2021, researchers analyzed the scientific traits of older vs. youthful adults presenting to an emergency division with self-reported fever following COVID-19 vaccination. The researchers checked out older sufferers as these aged 65 and older and youthful sufferers as these aged 19 to 64. Sufferers reporting signs greater than 2 weeks after vaccination had been excluded.
A complete of 562 sufferers had been included within the ultimate evaluation, of whom 396 (70.5%) had been girls, 155 (27.6%) had been 65 years and older, and most (>63.9%) had been admitted to an emergency division upon receipt first COVID-19 vaccine dose.
The speed of fever was lowered in older sufferers in comparison with youthful sufferers at emergency division admission (75.5% vs. 85.7%; P = 0.004) and aged sufferers had been extra doubtless to make use of emergency medical companies (43.9% vs. 18.7%; P <.001).
Though the timing of symptom onset after vaccination was comparable in older and youthful sufferers, older sufferers had been considerably extra prone to delay an emergency division go to (P =.004). As well as, whole admissions (32.9% vs. 4.2%), ICU admissions (7.1% vs. 1.0%), and median size of keep within the ED (3.5 vs. 2, Zero hours) in older vs. youthful sufferers (all P <.001). Aged sufferers who had been enrolled had been mostly recognized with urinary tract infections (27.5%), pneumonia (23.5%), hepatobiliary infections (15.7%), and gastrointestinal infections (13.7%).
A complete of 86 (83.5%) aged sufferers obtained a discharge analysis of an hostile occasion associated to the COVID-19 vaccination.
The research was restricted by its small pattern measurement, retrospective design, and doable choice bias. Different limitations included the usage of various kinds of COVID-19 vaccines and quick follow-up durations.
In response to the researchers, “Emergency [medicine] Physicians ought to think about not solely unwanted effects but additionally different infectious ailments in febrile older adults visiting the emergency division after COVID-19 vaccination.”
Jeong S, Hong S, Oh T, et al. Evaluation of older adults presenting to the emergency division with fever as a suspected vaccine-related hostile occasion of Covid-19: A retrospective multicenter research. J Chemother infect. Revealed on-line Might 2, 2022. doi:10.1016/j.jiac.2022.04.022