Do Cow Milk Casomorphins Contribute To Autism?

Casomorphins – breakdown merchandise of casein, a milk protein with opiate-like exercise – may help clarify why autism signs typically enhance with a dairy-free weight loss program.

In my final video sequence on autism and vitamin, I did talked about the advantages of broccoli sprouts, however the most typical educated Dietary and dietary interventions in autism and weight loss program embody variations on gluten-free and casein-free diets. Why?

Within the 1980s, a staff of distinguished Norwegian researchers developed reported an odd discovering. They in contrast the urine of kids with and with out autism within the hope of figuring out variations that may present clues as to the reason for autism. As you’ll be able to see at 0:42 in my video Autism and Casein from Cow’s Milk, a urine profile exhibits Spikes for every of the assorted parts. Normally the peptide area of the urine is fairly calm. Peptides are like little items of protein, and usually we should not be peeing out lots of protein. However there have been all types of peptide spikes within the urine profiles of kids with autism.

That distinction raised a query: “Can the pathophysiology” – that’s, the dysfunction – “of autism be defined by the character of the urine peptides found?” However first: “The place? to do did the peptides come from? ”They did not know, however there was a clue: Most dad and mom of kids with autism reported that their youngsters’s dysfunction worsened when uncovered to cow’s milk. In actual fact, two proteins – gluten, a protein in wheat and casein, a protein in milk – break down not solely into peptides, but additionally into exorphins.

Exorphins, opioid peptides derived from dietary proteins, “are referred to as exorphins due to their exogenous kind [that is, from outside of the body] Origin and morphine-like exercise ”, versus endorphins, that are morphine-like compounds that we produce in our physique. Possibly a few of these meals peptides represented a brand new class of hormones?

Nicely, was that the children? to pee out? Apparently as a result of a few of these peptides had opioid exercise. Maybe the researchers have been on to one thing.

Two forms of opioids have been used discovered in milk: casomorphins, “on account of their morphine-like exercise and their origin – they’re fragments of milk protein β-Casein “and the precise opiate morphine. It appears Be certainly Morphine in milk. That may not be a coincidence. “It is tough too imagine that these or different forms of opioids present in milk can not have any physiological or dietary significance. ”When you concentrate on it, it makes excellent sense. “Morphine and the opioid peptides can too to have performs an vital position within the mother-child bond mechanism, as infants might be “addicted” to their very own breast milk. ”However what about milk from one other species?

“Human milk is differs considerably from different mammals “in that it has the bottom casein content material. Moreover, human casein is a considerably totally different protein by way of its sequence of amino acid constructing blocks.

As you’ll be able to see in mine at 3:40 Video, human breast milk has over 15 occasions much less casein than cow’s milk and differs in its amino acid sequence by about half, making it breaks into peptides in another way. “Twenty-one peptides have been recognized from cow casein proteins,” together with a number of casomorphins, in comparison with solely 5 energetic peptides recognized in breast milk and just one casomorphin. As well as, “these” [casomorphins] from beef casein are stronger than β-Casomorphins from breast milk. “At 4:08 in mine Video, see a graph of opioid exercise, the place decrease means stronger. Was bovine casomorphine proven considerably stronger than the weak opioid peptide from gluten, a substance that’s extra corresponding to the casomorphin from human breast milk.

Certainly in case you do expose human nerve tissue to bovine casomorphine, it acts extra like morphine than the casomorphine from human breast milk with regard to epigenetic adjustments, adjustments in gene expression and never solely gives “a molecular justification for the advice of breastfeeding”. vs. [cows’ milk] Toddler formulation ”, but additionally a attainable one Rationalization why “casein-free, gluten-free diets” have been reported to alleviate a number of the gastrointestinal inflammatory and behavioral traits related to autism … “

“What is good for the goose could also be good for the gander, however what is sweet for the cow is perhaps good dangerous to people. “

This text discusses the primary video in a sequence in regards to the position of gluten and dairy free diets within the remedy of autism. Keep tuned for the opposite 5 movies on this six-part sequence:

My earlier sequence on autism was in regards to the superb story of broccoli sprouts being examined for the remedy of autistic boys. See:

Keep tuned to all of my autism associated movies Right here.

You may additionally be all for these movies on milk and toddler and toddler well being:

In well being,

Michael Greger, MD

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