Fusidic acid is an antibiotic.

It’s used to treat bacterial infections, such as skin infections (including cellulitis and impetigo), and eye infections (including conjunctivitis, also known as ‘red eye’).

Fusidic acid is only available on prescription.

It comes as a cream, ointment, or eye drops. Fusidic acid is combined with a steroid in some creams.

It’s also given by injection, as a liquid which you swallow, or as tablets, but these are usually only used in hospital.

Fusidic acid cream or ointment

  • It’s usual to use fusidic acid cream or ointment 3 or 4 times a day.
  • It’s unusual to get side effects with fusidic acid cream or ointment – but some people get skin irritation where they put it on.
  • Fusidic acid cream or ointment is called by the brand name Fucidin.

Fusidic acid eye drops

  • It’s usual to use fusidic acid eye drops twice a day.
  • The most common side effects of fusidic acid eye drops are dry, sore, itchy or stinging eyes. You may also get blurred vision.
  • Don’t wear contact lenses while you’re using fusidic acid eye drops – the drops can scratch or discolour them.
  • Fusidic acid eye drops are called by the brand name Fucithalmic.

Fusidic acid (cream, ointment and eye drops) can be used by most adults, including pregnant and breastfeeding women.

Fusidic acid can also be used by children.

Fusidic acid isn’t suitable for some people.

To make sure fusidic acid is safe for you, tell your doctor if
you have had an allergic reaction to fusidic acid or any other
medicines in the past.

It’s usual to put on fusidic acid cream or ointment 3 or 4 times a day. Check with your doctor or pharmacist if you’re unsure.

The difference between cream and ointment is that ointment is greasier. Your doctor will probably prescribe cream if you have a lot of infected skin to cover, and ointment for smaller infected areas.

How to put it on

  • Remove the cap. Check the seal isn’t broken before you first use the cream or ointment. Then push the spike in the cap through the seal on the tube.
  • Always wash your hands before using fusidic acid cream or ointment. Unless you’re using the cream or ointment to treat your hands, always wash your hands afterwards too.
  • Put a thin layer of cream or ointment onto the infected area and gently rub it in.
  • If you use it on your face be careful to avoid your eyes.

If you accidentally get any in your eye, wash it out with cold water straight away. Then bathe your eye with eyewash if possible. Your eye may sting. If you start to have any problems with your sight or your eye is sore, contact your doctor immediately.

If you’ve been told to cover the infected skin with any dressings or bandages, you may not need to use the medicine so often. Follow the advice of your doctor.

How long can I use it for?

Your skin should start to improve after a few days. But it’s very important to use the cream or ointment for as long as your doctor has prescribed it.

Treatment with fusidic cream or ointment is usually for 1 or 2 weeks, although sometimes, it can be for longer.

Fusidic acid eye drops come as a gel in a tube. As the gel touches your eye it becomes runnier.

It’s usual to put 1 drop into your eye twice a day, once in the morning and once in the evening.

How to put in eye drops

  • Take the cap off the tube when you’re ready to use the medicine. It’s important that the tip of the tube doesn’t touch your eye. If the tip of the tube touches your eye, squeeze out 2 or 3 drops straight away on to some tissue and rinse the tip of the tube with salt water.
  • Tilt your head back. Pull your lower eyelid down gently. Hold the tube over your eye and look up. Squeeze 1 drop into your lower eyelid.
  • Close your eye for a minute or two, and press gently on the side of your nose where the corner of your eye meets your nose. This helps to stop the drop from draining away and keeps it in your eye.

You might get some blurred vision straight after putting the drops in, but this should clear after a few minutes.

If the eye drops are for a child, it might be easier to put the drops in while they’re asleep or lying down.

If you normally wear contact lenses, wear your glasses instead until your symptoms have completely gone. Wait for 24 hours after the last dose of eye drops before using your contact lenses again. The eye drops can damage some contact lenses.

How long should I use eye drops for?

Your eye should start to feel better within a few days. But it’s very important to use the medicine for as long as your doctor has prescribed it. Even when your eye looks normal again, there may still be some bacteria in it.

As a general rule, you should use fusidic acid eye drops for at least 48 hours after you feel better and your eye looks normal. This will help to make sure that all the bacteria have been killed.

Side effects of cream or ointment

It’s unusual to have a side effect to fusidic acid cream or ointment.

Some people get skin irritation where they put on the cream or ointment. This happens in less than 1 in 100 people.

Keep using the cream or ointment, but talk to your doctor or pharmacist if skin irritation bothers you or doesn’t go away.

Serious side effects

Serious side effects of fusidic acid cream or ointment are rare and happen in less than 1 in 1,000 people. Tell a doctor straight away if you get:

  • conjunctivitis (red eye)
  • hives (red, itchy, raised areas of skin – also known as urticaria)

Side effects of eye drops

Common side effects of fusidic acid happen in more than 1 in 10 people and include:

  • burning, stinging, itching, soreness or dryness in the eye you are treating
  • blurred vision in the eye you are treating

Keep using the eye drops but talk to your doctor if they bother you or don’t go away.

Serious allergic reaction

In rare cases, it’s possible to have a serious allergic reaction to fusidic acid cream, ointment or eye drops.

What to do about:

Burning, stinging, itching, soreness or dryness in the eye you are treating
– do not rub your eye as this can make things worse. Wet a flannel with cool water and hold it over your eye for a few minutes to ease the symptoms. Make sure that you don’t share the flannel with others and wash it after you’ve used it. Always wash your hands after touching your eyes to stop the infection spreading.

It’s generally safe to use fusidic acid cream, ointment or eye drops while you’re pregnant or breastfeeding.

If you’re breastfeeding, take care when you put on fusidic acid cream or ointment to make sure you don’t accidentally get it on your breasts. If this happens, wash off any cream or ointment from your breasts before feeding your baby.

There aren’t any medicines known to cause problems if you take them at the same time as fusidic acid cream, ointment or eye drops.

How does fusidic acid work?